The NHMRC has funded the Brain-BaDGE project (PI: Gary Housley) at the TNF! Over the next four years, we will develop a platform for localized brain gene therapy, ‘Brain-BaDGE’, from proprietary UNSW electric field-focusing technology. This translational program will produce a first-for-human ‘needle-like’ medical device for electrotransfer of therapeutic DNA encoding a neuromodulator targeted to groups of neurons in the brain to suppress epileptic seizures of focal origin. This Brain-BaDGE platform will establish a translational pathway for gene therapies treating localized brain disorders.